Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660348 | 0.88 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29660366 | 0.84 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29911141 | 0.84 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29911227 | 0.84 | MMP13 (0.53) | RAB9ANPC1SMN1; SMN2MAPK1HPGD | |
| SCHEMBL29911267 | 0.82 | MMP13 (0.58) | RAB9ANPC1SMN1; SMN2MAPK1TLR7 | |
| SCHEMBL29911191 | 0.81 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL22940199 | 0.81 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL22939882 | 0.80 | MMP13 (0.62) | RAB9ANPC1TLR7MAPTGAA | |
| SCHEMBL22939716 | 0.80 | CDC25A (0.53) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL29911283 | 0.80 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | LIPC, LIPG, PNLIP | RAB9A 3552/4885NPC1 900/4885SMN1; SMN2 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.