Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675784 | 0.75 | BRD4 (0.35) | PAX8 | |
| SCHEMBL22940207 | 0.71 | MAP1LC3B (0.40) | — | |
| SCHEMBL22941341 | 0.71 | MAP1LC3B (0.40) | — | |
| SCHEMBL18666649 | 0.70 | BRD4 (0.35) | PAX8 | |
| SCHEMBL22941146 | 0.67 | MAP1LC3B (0.40) | — | |
| SCHEMBL22940441 | 0.67 | MAP1LC3B (0.40) | — | |
| SCHEMBL21986280 | 0.66 | BRD4 (0.38) | — | |
| SCHEMBL9934296 | 0.64 | BRD4 (0.40) | PAX8 | |
| SCHEMBL7911235 | 0.61 | KDM4E (0.38) | — | |
| SCHEMBL7850519 | 0.60 | TNF (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018018-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INIDBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2021-02-04 | — | — | WO | disclosed |