SCHEMBL229418

SCHEMBL229418

CCN(Cc1ccc(Cl)nc1)c1nc(=O)on1C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
GAA P10253 2/20 0.35
PDE2A O00408 1/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL759593 0.87 ALDH1A1 (0.33) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL231801 0.86 MEN1 (0.34) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL230489 0.86 ALDH1A1 (0.35) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL231494 0.85 GAA (0.39) MAPTALDH1A1LMNAKMT2AGAA
SCHEMBL231942 0.80 ALDH1A1 (0.37) ALDH1A1MEN1KMT2A
SCHEMBL230649 0.71 ALDH1A1 (0.36) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL29572122 0.71 ALDH1A1 (0.36) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL2893249 0.70 ALDH1A1 (0.35) MAPTALDH1A1MEN1LMNAKMT2A
SCHEMBL231495 0.70 CYP3A4 (0.39) MAPTMEN1KMT2AGAAKDM4E
SCHEMBL229419 0.68 P2RX3 (0.35) MAPTALDH1A1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 US claimed
EP-2587922-A1 IMPROVED INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES Bayer Intellectual Property GmbH (DE) 2013-05-08 EP disclosed
WO-2012000902-A1 IMPROVED INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 WO disclosed
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES DDT, PRMT9, PNISR MAPT 3876/4885ALDH1A1 4218/4885MEN1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.