SCHEMBL229419

SCHEMBL229419

CC(Cc1ccc(Cl)nc1)Nc1nc(=O)on1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 1/20 0.35
ALDH1A1 P00352 1/20 0.34
ATM Q13315 2/20 0.34
KMT2A Q03164 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
MEN1 O00255 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231495 0.78 CYP3A4 (0.39) KMT2AMEN1L3MBTL1KDM4EGAA
SCHEMBL229979 0.75 ALDH1A1 (0.34) P2RX3ALDH1A1ATMKMT2ACHRNB2
SCHEMBL231943 0.74 MEN1 (0.34) ALDH1A1ATMKMT2ACHRNB2CHRNA4
SCHEMBL230650 0.71 LMNA (0.36) ALDH1A1ATMKMT2AMEN1L3MBTL1
SCHEMBL231494 0.70 GAA (0.39) ALDH1A1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL5040772 0.70 TAAR1 (0.48) ALDH1A1L3MBTL1KDM4EGAAMAPT
SCHEMBL229418 0.68 MAPT (0.35) ALDH1A1KMT2AMEN1L3MBTL1LMNA
SCHEMBL5048177 0.68 SIGMAR1 (0.51) ALDH1A1L3MBTL1LMNAKDM4EGAA
SCHEMBL231801 0.68 MEN1 (0.34) ALDH1A1ATMKMT2AMEN1L3MBTL1
SCHEMBL8245704 0.66 ALDH1A1 (0.47) ALDH1A1L3MBTL1LMNAKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 US claimed
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES BAYER CROPSCIENCE AG (DE) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004268-A1 INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES DDT, PRMT9, PNISR P2RX3 1079/4885ALDH1A1 4218/4885ATM 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.