Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22947458 | 0.95 | PTPRC (0.38) | PTPRCAHRCYP2A6S100A4POLB | |
| SCHEMBL21123265 | 0.80 | PTPRC (0.39) | PTPRCAHRCYP2A6S100A4POLB | |
| SCHEMBL11984775 | 0.79 | PTPRC (0.40) | PTPRCAHRCYP2A6S100A4ALDH1A1 | |
| SCHEMBL22947461 | 0.76 | PTPRC (0.44) | PTPRCAHRCYP2A6S100A4MAPK1 | |
| SCHEMBL21695235 | 0.74 | S100A4 (0.41) | PTPRCAHRCYP2A6S100A4ALDH1A1 | |
| SCHEMBL15935730 | 0.74 | GPR3 (0.44) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL26017216 | 0.72 | PTPRC (0.40) | PTPRCCYP2A6S100A4ALDH1A1MAPK1 | |
| SCHEMBL22947629 | 0.72 | ALDH1A1 (0.39) | PTPRCAHRALDH1A1MAPK1 | |
| SCHEMBL11984776 | 0.72 | PTPRC (0.33) | PTPRCAHRCYP2A6 | |
| SCHEMBL22949059 | 0.67 | CYP2A6 (0.55) | PTPRCAHRCYP2A6ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | PTPRC 3228/4885AHR 33/4885CYP2A6 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.