Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PAM | P19021 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980701 | 0.98 | L3MBTL1 (0.59) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL15820218 | 0.98 | L3MBTL1 (0.59) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| Ammonia Solution, Strong SCHEMBL28260174 | 0.98 | L3MBTL1 (0.59) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL27749803 | 0.84 | ALDH1A1 (0.48) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL248113 | 0.81 | ALDH1A1 (0.65) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| Benzene SCHEMBL9407299 | 0.81 | ALDH1A1 (0.65) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL664857 | 0.81 | ALDH1A1 (0.65) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL18269361 | 0.80 | LOXL2 (0.47) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL999003 | 0.80 | ALDH1A1 (0.42) | L3MBTL1MAPK1ALDH1A1PAMTSHR | |
| SCHEMBL16066069 | 0.80 | CA2 (0.59) | L3MBTL1MAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698308-B | Synthesis method of bromfenac sodium | 山东辰龙药业有限公司 | 2024-06-21 | — | — | CN | claimed |
| US-20220220144-A1 | MULTIMERIC PAN-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2022-07-14 | — | — | US | claimed |
| CN-112500325-A | Alpha, omega-type chain transfer agent for reversible addition-fragmentation chain transfer RAFT polymerization, and preparation method and application thereof | 北京吉乃尔科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| WO-2020219419-A1 | MULTIMERIC PAN–SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2020-10-29 | — | — | WO | claimed |
| CN-106946770-B | High-activity imido phenylacetate compound and preparation method and application thereof | 中国农业大学 | 2020-05-05 | — | — | CN | claimed |
| CN-109705088-A | A kind of preparation method of Egelieting intermediate | 深圳市第二人民医院 | 2019-05-03 | — | — | CN | claimed |
| CN-108947861-A | The synthetic method of C14H10Cl2NNaO2 | 复旦大学 | 2018-12-07 | — | — | CN | claimed |
| CN-107973742-A | The method for preparing 3- indole ketone compounds | 重庆文理学院 | 2018-05-01 | — | — | CN | claimed |
| CN-104284891-B | Conformationally constrained, fully synthetic macrocyclic compounds | 波利弗尔股份公司 | 2018-04-17 | — | — | CN | claimed |
| EP-2264043-B1 | Heterobifunctional pan-selectin inhibitors | GLYCOMIMETICS INC (US) | 2017-11-08 | — | — | EP | claimed |
| US-20120004190-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GLYCOMIMETICS, INC. (US) | 2012-01-05 | — | — | US | claimed |
| US-7989601-B2 | Heterobifunctional pan-selectin inhibitors | GLYCOMIMETICS, INC. (US) | 2011-08-02 | — | — | US | claimed |
| EP-2264043-A1 | Heterobifunctional pan-selectin inhibitors | GlycoMimetics, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| US-20100204170-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GLYCOMIMETICS, INC. (US) | 2010-08-12 | — | — | US | claimed |
| CN-101525603-A | Immobilized alpha-amino-acid ester hydrolase, preparation and application thereof | SICHUAN IND I OF ANTIBIOTICS C | 2009-09-09 | — | — | CN | claimed |
| US-20090036386-A1 | Heterobifunctional compounds for selectin inhibition | GLYCOMIMETICS, INC (US) | 2009-02-05 | — | — | US | claimed |
| EP-1934236-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GlycoMimetics, Inc. (US) | 2008-06-25 | — | — | EP | claimed |
| US-20070054870-A1 | glycomimetics; selectin binding modulators for use in treatment ofinflammatory, autoimmune, infection, cancer, shock, thrombosis, wounds, burns, reperfusion injury, blood, leukocyte-mediated lung injury, spinal cord damage, digestive tract mucous membrane disorders, osteoporosis, arthritis and asthma | GLYCOMIMETICS, INC. (US) | 2007-03-08 | — | — | US | claimed |
| WO-2007028050-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GLYCOMIMETICS, INC. (US) | 2007-03-08 | — | — | WO | claimed |
| WO-2006127906-A1 | HETEROBIFUNCTIONAL COMPOUNDS FOR SELECTIN INHIBITION | GLYCOMIMETICS, INC. (US) | 2006-11-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036386-A1 | Heterobifunctional compounds for selectin inhibition | SELE, SELL, BSG | L3MBTL1 2197/4885MAPK1 2943/4885ALDH1A1 592/4885 |
| US-20120004190-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | SELE, SELP, BSG | L3MBTL1 2309/4885MAPK1 2943/4885ALDH1A1 679/4885 |
| US-20070054870-A1 | glycomimetics; selectin binding modulators for use in treatment ofinflammatory, autoimmune, infection, cancer, shock, thrombosis, wounds, burns, reperfusion injury, blood, leukocyte-mediated lung injury, spinal cord damage, digestive tract mucous membrane disorders, osteoporosis, arthritis and asthma | BSG, SELE, SELL | L3MBTL1 550/4885MAPK1 1844/4885ALDH1A1 1896/4885 |
| US-20100204170-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | SELE, SELP, BSG | L3MBTL1 2309/4885MAPK1 2943/4885ALDH1A1 679/4885 |
| US-20220220144-A1 | MULTIMERIC PAN-SELECTIN ANTAGONISTS | SELE, SELP, BSG | L3MBTL1 2261/4885MAPK1 3411/4885ALDH1A1 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.