Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20039982 | 0.86 | ESR1 (0.41) | IDO1L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL18982972 | 0.84 | RXRA (0.57) | IDO1L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL31003340 | 0.83 | PGR (0.41) | LMNAL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL27473073 | 0.83 | L3MBTL1 (0.37) | IDO1L3MBTL1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31577514 | 0.81 | ADRB2 (0.43) | IDO1L3MBTL1KMT2AKDM5BESR1 | |
| SCHEMBL14370178 | 0.81 | ALDH1A1 (0.40) | L3MBTL1NPC1RAB9AESR1ESR2 | |
| SCHEMBL2154504 | 0.80 | KMT2A (0.47) | LMNAL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL22349666 | 0.79 | L3MBTL1 (0.35) | L3MBTL1KMT2ANPC1RAB9AKDM5B | |
| SCHEMBL8992978 | 0.79 | MAOB (0.42) | L3MBTL1KMT2ANPC1RAB9AESR1 | |
| SCHEMBL22604441 | 0.78 | ESR1 (0.46) | LMNAL3MBTL1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322747-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| WO-2023196605-A1 | INHIBITING HISTONE DEACETYLASE 6 (HDAC6) | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196601-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-11708346-B2 | Treatment and prevention of neuropathic pain with P2Y14 antagonists | SAINT LOUIS UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708346-B2 | Treatment and prevention of neuropathic pain with P2Y14 antagonists | SAINT LOUIS UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
| US-11584736-B2 | Heterocyclic P2Y14 receptor antagonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220411383-A1 | AMINOPYRAZINE DERIVATIVES AS PI3K-y INHIBITORS | INCYTE CORPORATION | 2022-12-29 | — | — | US | disclosed |
| US-20220395506-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | INCYTE CORPORATION | 2022-12-15 | — | — | US | disclosed |
| US-4459224-A | Perfume compositions as well as perfumed articles and materials containing alkyl substituted benzyl cyanides as a fragrance | NAARDEN INTERNATIONAL N.V. (NL) | 1984-07-10 | — | — | US | disclosed |
| EP-0047562-B1 | METHOD FOR THE PRODUCTION OF ALKYL AND ALKOXYALKYL SUBSTITUTED BENZENE COMPOUNDS | STAUFFER CHEMICAL COMPANY (US) | 1983-11-23 | — | — | EP | disclosed |
| EP-0062368-A1 | Perfume compositions as well as perfumed products containing alkyl substituted benzyl cyanides as a fragrance | NAARDEN INTERNATIONAL N.V. (NL) | 1982-10-13 | — | — | EP | disclosed |
| EP-0047562-A1 | Method for the production of alkyl and alkoxyalkyl substituted benzene compounds | STAUFFER CHEMICAL COMPANY (US) | 1982-03-17 | — | — | EP | disclosed |
| US-4260760-A | BACTERICIDES, ALGICIDES | MERCK & CO., INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4172094-A | Polyamine compounds | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4079059-A | ANTIMICROBIAL, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1978-03-14 | — | — | US | disclosed |
| US-4070400-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4061775-A | Polyamine compounds as antibacterial agents | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4058624-A | Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322747-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC11 | IDO1 1505/4885PYCR1 3322/4885LMNA 4281/4885 |
| US-11708346-B2 | Treatment and prevention of neuropathic pain with P2Y14 antagonists | P2RY14, P2RY4, P2RY13 | IDO1 3238/4885PYCR1 3684/4885LMNA 3507/4885 |
| US-20220395506-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | JAK3, JAK1, JAK2 | IDO1 419/4885PYCR1 407/4885LMNA 4785/4885 |
| US-11584736-B2 | Heterocyclic P2Y14 receptor antagonists | P2RY14, P2RY1, P2RY13 | IDO1 2869/4885PYCR1 518/4885LMNA 3348/4885 |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | JAK3, JAK1, JAK2 | IDO1 419/4885PYCR1 407/4885LMNA 4785/4885 |
| US-20220411383-A1 | AMINOPYRAZINE DERIVATIVES AS PI3K-y INHIBITORS | PIK3R5, PIK3CD, PIK3CG | IDO1 933/4885PYCR1 2266/4885LMNA 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.