Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955526 | 0.92 | KDR (0.65) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL22955364 | 0.89 | HPGD (0.55) | HPGDKDM4EALDH1A1MAPTHTR2C | |
| SCHEMBL22955351 | 0.88 | MEN1 (0.59) | HPGDKDM4EHTR2CMEN1KMT2A | |
| SCHEMBL22955525 | 0.88 | KDR (0.42) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL20765466 | 0.84 | ALDH1A1 (0.64) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL5952108 | 0.82 | FGFR1 (0.58) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL22955692 | 0.81 | MGLL (0.53) | KDRFGFR1PDGFRBHPGDALDH1A1 | |
| SCHEMBL2310280 | 0.80 | KDR (0.50) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL13042446 | 0.80 | KDR (0.58) | KDRFGFR1PDGFRBHPGDTSHR | |
| SCHEMBL22955686 | 0.80 | RAB9A (0.53) | HPGDKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |