Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955544 | 0.88 | GAA (0.40) | SMN1; SMN2MAPTALDH1A1CYP3A4KMT2A | |
| SCHEMBL22955560 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTALDH1A1TSHRKMT2A | |
| SCHEMBL22954932 | 0.78 | CTH (0.34) | MAPT | |
| SCHEMBL22955558 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL22955543 | 0.73 | RAB9A (0.41) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL22955449 | 0.73 | POLB (0.30) | KMT2A | |
| SCHEMBL22955549 | 0.72 | RECQL (0.35) | MAPT | |
| SCHEMBL19531289 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL7419984 | 0.70 | ALDH1A1 (0.70) | MAPTALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL22955551 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1TSHRKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018833-A1 | CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |