Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954945 | 0.92 | MEN1 (0.44) | ACHEGRM5POLBALDH1A1L3MBTL1 | |
| SCHEMBL22955567 | 0.90 | CHRNB2 (0.41) | ACHEGRM5POLBHTTALDH1A1 | |
| SCHEMBL22955948 | 0.85 | GAA (0.44) | EPHX1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL22955446 | 0.85 | SLC9A1 (0.33) | HTTALDH1A1 | |
| SCHEMBL22954942 | 0.83 | CNR1 (0.34) | POLBHTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL22954989 | 0.82 | ALDH1A1 (0.33) | HTTALDH1A1DPP4 | |
| SCHEMBL21344670 | 0.82 | CHRM2 (0.42) | ACHEGRM5POLBHTTALDH1A1 | |
| SCHEMBL22954938 | 0.81 | — | — | |
| SCHEMBL22954921 | 0.80 | GPR119 (0.47) | KMT2AMEN1KDM4E | |
| SCHEMBL22954940 | 0.80 | LMNA (0.38) | GRM5SMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018833-A1 | CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |