Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | NPY2R | P49146 | 1/20 | 0.65 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957846 | 0.83 | NPY1R (0.70) | NPY1RNPY2RKCNH2EPHX2MEN1 | |
| SCHEMBL22957841 | 0.83 | NPY1R (0.47) | NPY1RNPY2RCARM1PRMT1HTT | |
| SCHEMBL22957689 | 0.83 | CARM1 (0.59) | NPY1RNPY2RCARM1PRMT1SLC6A2 | |
| SCHEMBL22957770 | 0.82 | NPY1R (0.46) | NPY1RNPY2RHTTRIPK1 | |
| SCHEMBL22957842 | 0.81 | CARM1 (0.61) | NPY1RNPY2RCARM1PRMT1SLC6A4 | |
| SCHEMBL22957672 | 0.81 | RIPK1 (0.60) | NPY1RNPY2RHTTUSP2CYP1A2 | |
| SCHEMBL22957686 | 0.80 | NPY1R (0.53) | NPY1RNPY2RCARM1PRMT1USP2 | |
| SCHEMBL22957692 | 0.80 | LMNA (0.54) | NPY1RNPY2RCARM1PRMT1HRH1 | |
| SCHEMBL22390612 | 0.80 | RIPK1 (0.58) | NPY1RNPY2RCARM1PRMT1SLC6A2 | |
| SCHEMBL15073171 | 0.77 | CARM1 (0.55) | NPY1RNPY2RCARM1PRMT1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | NPY1R 2919/4885NPY2R 3582/4885CARM1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.