SCHEMBL22960296

SCHEMBL22960296

CC(C)(C)c1nc(-c2ccccn2)c2ccc3ccccc3c2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
NPC1 O15118 3/20 0.45
MAPT P10636 3/20 0.45
TP53 P04637 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
RAB9A P51151 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TGFBR1 P36897 4/20 0.41
LRRK2 Q5S007 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
AHR P35869 1/20 0.36
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24731790 0.87 NPC1 (0.41) KDM4ENPC1MAPTTP53SMN1; SMN2
SCHEMBL24731956 0.80 RAB9A (0.49) KDM4ENPC1MAPTRAB9AALDH1A1
SCHEMBL19161960 0.80 MAOA (0.40) KDM4ENPC1MAPTSMN1; SMN2RAB9A
SCHEMBL18132503 0.78 KDM4E (0.48) KDM4ENPC1MAPTTP53SMN1; SMN2
SCHEMBL19162668 0.77 MAOA (0.38) KDM4EMAPTALDH1A1HPGDCYP1A2
SCHEMBL19162667 0.76 MAPT (0.40) KDM4ENPC1MAPTSMN1; SMN2RAB9A
SCHEMBL25878131 0.75 ALDH1A1 (0.37) KDM4EMAPTTP53SMN1; SMN2ALDH1A1
SCHEMBL22097079 0.74 L3MBTL1 (0.42) NPC1MAPTRAB9AALDH1A1HPGD
SCHEMBL25878190 0.74 L3MBTL1 (0.46) NPC1MAPTRAB9AALDH1A1HPGD
SCHEMBL23473872 0.74 MAOA (0.39) KDM4EMAPTALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed
US-11524967-B2 Heteroacene and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-12-13 US disclosed
US-20220255013-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-08-11 US disclosed
US-20210040112-A1 HETEROACENE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2021-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220255013-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, SLCO2A1, SLCO2B1 KDM4E 2765/4885NPC1 603/4885MAPT 1041/4885
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, ODC1, OTC KDM4E 2552/4885NPC1 1403/4885MAPT 1823/4885
US-11524967-B2 Heteroacene and organic electroluminescence device using the same POF1B, HCN1, HCN2 KDM4E 3655/4885NPC1 2350/4885MAPT 1933/4885
US-20210040112-A1 HETEROACENE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME HCN1, HCN2, CACNA1F KDM4E 3762/4885NPC1 1912/4885MAPT 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.