SCHEMBL22965627

SCHEMBL22965627

CCCC(=O)OCCNC(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TOP2A P11388 1/20 0.39
GLA P06280 1/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA1A P35348 1/20 0.36
DNM1 Q05193 1/20 0.36
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.35
EPHX2 P34913 1/20 0.35
BLM P54132 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17036668 0.89 DGKA (0.44) DGKAALDH1A1MAPTKDM4EDNM1
SCHEMBL22652916 0.84 NAAA (0.45) ALDH1A1MAPTKDM4EPOLBTDP1
SCHEMBL11190223 0.83 DGKA (0.50) DGKAALDH1A1MAPTDNM1LMNA
SCHEMBL16858306 0.83 CA1 (0.38) DGKAALDH1A1MAPTKDM4EHSD17B10
SCHEMBL27847936 0.80 ALDH1A1 (0.44) DGKAALDH1A1MAPTKDM4ETDP1
SCHEMBL22340363 0.78 MMP1 (0.37) ALDH1A1KDM4EPOLBTDP1
SCHEMBL16858346 0.78 DGKA (0.47) DGKAALDH1A1TOP2AGLAMAPT
SCHEMBL7309740 0.78 GAA (0.52) ALDH1A1TOP2AKDM4EPOLB
SCHEMBL22134307 0.77 CYP19A1 (0.42) DGKAALDH1A1MAPTKDM4EHSD17B10
SCHEMBL8924001 0.77 ADRA2A (0.36) DGKAALDH1A1GLAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236387-B2 Compositions and methods for nucleic acid sequencing Singular Genomics Systems, Inc. (US) 2022-02-01 US disclosed
US-20210040555-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING FIRST-CITIZENS BANK & TRUST COMPANY 2021-02-11 US disclosed