SCHEMBL22969348

SCHEMBL22969348

c1ccc2c(c1)Sc1cccc3c(-c4c5ccccc5c(-c5ccc(-c6cccc7ccccc67)cc5)c5ccccc45)ccc-2c13

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA9 Q16790 4/20 0.38
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PPARG P37231 8/20 0.36
PPARA Q07869 8/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
PPARD Q03181 1/20 0.36
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
TYMS P04818 1/20 0.34
DHFR P00374 1/20 0.34
CYP1A2 P05177 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969195 0.99 ENPP3 (0.37) ENPP3ENPP1CA12CA1CA2
SCHEMBL16558469 0.90 CRHBP (0.33) ENPP3ENPP1CYP2C19TYMSCYP1A2
SCHEMBL22969349 0.90 MCL1 (0.34) ENPP3ENPP1CA12CA1CA2
SCHEMBL22969343 0.89 PDCD1 (0.36) ENPP1PPARGPPARACYP2C9CYP2C19
SCHEMBL22969190 0.88 MCL1 (0.33) ENPP3ENPP1CA12CA1CA2
SCHEMBL22969179 0.87 PDCD1 (0.35) ENPP1PPARGPPARACYP2C9CYP2C19
SCHEMBL22969357 0.87 ALDH1A1 (0.37) CA12CA1CA2CA9TYMS
SCHEMBL22969342 0.87 ACHE (0.33) TYMSMCL1
SCHEMBL22969353 0.87 ACHE (0.35) ENPP1CYP2C19TYMS
SCHEMBL22969196 0.86 ANPEP (0.36) CA12CA1CA2CA9TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021025163-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE USING SAME 出光興産株式会社 2021-02-11 WO disclosed
WO-2021025162-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME, AND ELECTRONIC APPLIANCE 出光興産株式会社 2021-02-11 WO disclosed