Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22970094 | 0.94 | TACR1 (0.39) | TACR1SIRT1SIRT2CALCRLPTGER4 | |
| SCHEMBL22969940 | 0.92 | OPRL1 (0.42) | SIRT1SIRT2CALCRLOPRL1ITGB1 | |
| SCHEMBL23180468 | 0.91 | TACR1 (0.35) | TACR1SIRT1SIRT2CALCRLPTGER4 | |
| SCHEMBL22969857 | 0.91 | NPY4R (0.41) | SIRT1SIRT2CALCRLOPRL1ITGB1 | |
| SCHEMBL25100624 | 0.89 | OPRK1 (0.37) | TACR1SIRT1SIRT2PTGER4OPRL1 | |
| SCHEMBL25100623 | 0.88 | TACR1 (0.39) | TACR1SIRT1SIRT2CALCRLPTGER4 | |
| SCHEMBL22969859 | 0.85 | KDM1A (0.43) | SIRT1SIRT2OPRK1KDM1AMAOA | |
| SCHEMBL25100620 | 0.83 | TACR1 (0.36) | TACR1SIRT1SIRT2OPRL1OPRK1 | |
| SCHEMBL13477993 | 0.82 | CALCRL (0.49) | CALCRLOPRL1OPRK1ITGB1ITGA4 | |
| SCHEMBL22970116 | 0.81 | MAP1LC3B (0.40) | SIRT1SIRT2OPRL1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022678-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-02-11 | — | — | WO | disclosed |