Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.62 |
| ▸ | PRKCG | P05129 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCB | P05771 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol SCHEMBL22973790 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL64353 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL28866474 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27299282 | 0.98 | PRKCA (0.63) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27478115 | 0.94 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL28465138 | 0.94 | PRKCA (0.56) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27450792 | 0.93 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL23610504 | 0.92 | PRKCA (0.61) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27579226 | 0.92 | PRKCA (0.67) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL7566989 | 0.92 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073422-B | Semi-synthesis method for 12-deoxyphorbol-13-acetate, prostratin | UNIV QIQIHAR | 2014-09-03 | — | — | CN | claimed |
| CN-103086886-A | Semisynthesis method of 12-deoxyphorbol-13-phenylacetate (DPP) | UNIV QIQIHAR | 2013-05-08 | — | — | CN | claimed |
| CN-103073422-A | Semi-synthesis method for 12-deoxyphorbol-13-acetate, prostratin | UNIV QIQIHAR | 2013-05-01 | — | — | CN | claimed |
| CN-103073422-B | Semi-synthesis method for 12-deoxyphorbol-13-acetate, prostratin | UNIV QIQIHAR | 2014-09-03 | — | — | CN | disclosed |
| CN-101573449-B | DNA vaccine for treating chronic hepatitis B and preparation method thereof | POSTECH FOUNDATION | 2013-09-18 | — | — | CN | disclosed |
| CN-103086886-A | Semisynthesis method of 12-deoxyphorbol-13-phenylacetate (DPP) | UNIV QIQIHAR | 2013-05-08 | — | — | CN | disclosed |
| CN-103073422-A | Semi-synthesis method for 12-deoxyphorbol-13-acetate, prostratin | UNIV QIQIHAR | 2013-05-01 | — | — | CN | disclosed |
| CN-101573449-A | DNA vaccine for treating chronic hepatitis B and preparation method thereof | POSTECH FOUNDATION (KR) | 2009-11-04 | — | — | CN | disclosed |
| CN-1227265-C | Antibodies against CCR5 | HUMAN GENOME SCIENCES INC (US) | 2005-11-16 | — | — | CN | disclosed |
| CN-1564826-A | Human G-protein chemokine receptor (CCR5) HDGNR10 | HUMAN GENOME SCIENCES INC (US) | 2005-01-12 | — | — | CN | disclosed |
| CN-1454216-A | Antibodies to CCR5 | HUMAN GENOME SCIENCES INC (US) | 2003-11-05 | — | — | CN | disclosed |
| CN-1385529-A | Expression system utilizing self-schizolysis fusing protein and novel reduction polypeptide | SANKYO CO (JP) | 2002-12-18 | — | — | CN | disclosed |
| CN-1385532-A | Expression system utilizing self-schizolysis fusing protein and novel reduction polypeptide | SANKYO CO (JP) | 2002-12-18 | — | — | CN | disclosed |
| CN-1090676-C | Expression system using self-lysis fusion protein and novel reduced polypeptide | SANKYO CO (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1320689-A | Expression system using autotomy of fusion protein, and reduced polypeptide | SANKYO CO (JP) | 2001-11-07 | — | — | CN | disclosed |
| CN-1126759-A | Expression system using self-lysis fusion protein and novel reduced polypeptide | SANKYO CO (JP) | 1996-07-17 | — | — | CN | disclosed |