SCHEMBL22975002

SCHEMBL22975002

Oc1cc(N2CCCc3ccccc32)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
THRB P10828 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ROCK1 Q13464 1/20 0.38
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.38
KDM4C Q9H3R0 1/20 0.38
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
STAT3 P40763 1/20 0.37
AKT1 P31749 1/20 0.37
PIK3CA P42336 1/20 0.37
NUDT1 P36639 1/20 0.37
NOTUM Q6P988 1/20 0.37
MGLL Q99685 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065653 1.00 LMNA (0.39) LMNATHRBSIGMAR1SMN1; SMN2ROCK1
SCHEMBL17452173 0.85 ALDH1A1 (0.46) LMNASIGMAR1SMN1; SMN2ROCK1ALDH1A1
SCHEMBL15790934 0.80 L3MBTL1 (0.42) LMNATHRBSIGMAR1SMN1; SMN2ROCK1
SCHEMBL23908719 0.80 ROCK1 (0.43) SIGMAR1SMN1; SMN2ROCK1KMT2AMEN1
SCHEMBL15790987 0.80 L3MBTL1 (0.42) LMNATHRBSIGMAR1SMN1; SMN2ROCK1
SCHEMBL31410785 0.79 MEN1 (0.44) LMNASIGMAR1SMN1; SMN2ROCK1ALDH1A1
SCHEMBL31410786 0.79 MEN1 (0.44) LMNASIGMAR1SMN1; SMN2ROCK1ALDH1A1
SCHEMBL23908720 0.79 MEN1 (0.44) LMNASIGMAR1SMN1; SMN2ROCK1ALDH1A1
SCHEMBL13426500 0.78 EED (0.40) LMNATHRBSIGMAR1SMN1; SMN2ROCK1
SCHEMBL22989391 0.78 ALDH1A1 (0.38) ALDH1A1HPGDKDM4CKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839151-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-05 US disclosed
US-11839151-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-05 US disclosed
US-11839151-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-05 US disclosed
EP-3778610-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2022-12-14 EP disclosed
US-20210050525-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-18 US disclosed
US-20210050525-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-18 US disclosed
EP-3778610-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839151-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device LEF1, PIEZO1, OCIAD1 LMNA 1501/4885THRB 4489/4885SIGMAR1 2411/4885
US-20210050525-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, PIEZO1, OCIAD1 LMNA 1501/4885THRB 4489/4885SIGMAR1 2411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.