SCHEMBL22978939

SCHEMBL22978939

NOC1(N)C=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 6/20 0.41
▸ SLC28A1 O00337 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ SLC29A1 Q99808 1/20 0.41
▸ SLC28A3 Q9HAS3 1/20 0.41
▸ LMNA P02545 3/20 0.39
▸ MTOR P42345 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ THRB P10828 1/20 0.39
▸ MDM2 Q00987 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ DNMT1 P26358 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845228 0.90 CDA (0.41) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL6906558 0.85 LMNA (0.45) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3630509 0.85 LMNA (0.45) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25188377 0.84 CDA (0.43) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25382397 0.83 CDA (0.38) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL10903345 0.82 CDA (0.42) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL31436719 0.82 CDA (0.42) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL4751008 0.81 LMNA (0.42) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27845966 0.81 CDA (0.41) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL17440122 0.81 CDA (0.41) CDASLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR Stemirna Therapeutics Co., Ltd. (CN) 2023-07-13 — — US disclosed
WO-2021027614-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR 斯微(上海)生物科技有限公司 2021-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR RNMT, RNGTT, BCDIN3D CDA 9/4885SLC28A1 142/4885SLC28A2 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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