Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.84 |
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336785 | 0.87 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6793571 | 0.84 | RAB9A (0.76) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL24933360 | 0.83 | RAB9A (0.73) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6174341 | 0.82 | TSHR (0.75) | ALDH1A1MAPTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL12135284 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL259177 | 0.81 | TDP1 (0.78) | ALDH1A1SMN1; SMN2RAB9ANPC1TSHR | |
| SCHEMBL26962799 | 0.81 | ALDH1A1 (0.76) | ALDH1A1MAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL3637836 | 0.81 | HDAC3 (0.65) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| Ethyl Nicotinate SCHEMBL24853 | 0.81 | L3MBTL1 (0.71) | ALDH1A1MAPTKDM4ELMNAMAPK1 | |
| Ethyl Nicotinate SCHEMBL8164637 | 0.81 | L3MBTL1 (0.71) | ALDH1A1MAPTKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324899-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | METRO INTERNATIONAL BIOTECH, LLC | 2022-10-13 | — | — | US | disclosed |
| EP-4013766-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | Metro International Biotech, LLC (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030551-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | METRO INTERNATIONAL BIOTECH, LLC (US) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324899-A1 | COMPOUNDS AND COMPOSITIONS FOR DIFFERENTIAL MODULATION OF NICOTINAMIDE ADENINE DINUCLEOTIDE | NQO1, NAMPT, NADK | ALDH1A1 733/4885MAPT 2172/4885SMN1; SMN2 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.