Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 5/20 | 0.47 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964189 | 1.00 | DHFR (0.52) | DHFRTK1NT5MALBPKM | |
| SCHEMBL22984005 | 1.00 | DHFR (0.52) | DHFRTK1NT5MALBPKM | |
| SCHEMBL8514886 | 0.88 | TK1 (0.46) | DHFRTK1NT5MBLMPMP22 | |
| SCHEMBL12296875 | 0.83 | DHFR (0.39) | DHFRTK1 | |
| SCHEMBL16503451 | 0.83 | DUT (0.36) | DHFR | |
| SCHEMBL7859796 | 0.81 | TK1 (0.38) | DHFRTK1 | |
| SCHEMBL21886783 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM | |
| SCHEMBL21886782 | 0.81 | DHFR (0.39) | DHFRTK1ALBLMNABLM | |
| SCHEMBL21886784 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM | |
| SCHEMBL2113192 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331106-B1 | NUCLEOSIDE ANALOGUES USEFUL AS POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS | IMP INNOVATIONS LTD (GB) | 2012-10-10 | — | — | EP | disclosed |
| US-20110236312-A1 | NUCLEOSIDE ANALOGUES USEFUL AS POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236312-A1 | NUCLEOSIDE ANALOGUES USEFUL AS POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS | TYMP, SLC29A1, NT5C3B | DHFR 289/4885TK1 16/4885NT5M 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.