Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244819 | 0.89 | HTT (0.64) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6250449 | 0.86 | SMN1; SMN2 (0.43) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL22987099 | 0.86 | HTT (0.41) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15818528 | 0.84 | KDM4E (0.49) | HPGDALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL28190043 | 0.82 | CA12 (0.40) | RAB9AHTTHSD17B10MEN1KMT2A | |
| SCHEMBL31321274 | 0.82 | HTT (0.55) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3035651 | 0.82 | ALDH1A1 (0.42) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL133355 | 0.81 | AGER (0.58) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31744674 | 0.80 | ALDH1A1 (0.59) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4215084 | 0.80 | SMN1; SMN2 (0.43) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925848-B2 | Amide derivative | IDO1, IDO2, TPH1 | HPGD 550/4885ALDH1A1 750/4885KDM4E 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.