Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300805 | 0.87 | KDM4E (0.34) | KDM4E | |
| SCHEMBL2297928 | 0.85 | DPP4 (0.31) | KDM4E | |
| SCHEMBL25700656 | 0.77 | HRH4 (0.33) | — | |
| SCHEMBL2294529 | 0.77 | GLB1 (0.33) | — | |
| SCHEMBL2297692 | 0.77 | TDP1 (0.41) | KDM4E | |
| SCHEMBL2296528 | 0.75 | SIGMAR1 (0.33) | — | |
| SCHEMBL2297096 | 0.75 | ATM (0.37) | — | |
| SCHEMBL2301494 | 0.75 | PDK1 (0.33) | — | |
| SCHEMBL2295851 | 0.75 | CYP2C9 (0.38) | — | |
| SCHEMBL2300211 | 0.75 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999006-B2 | Anticancer agents; mitogen-activated protein kinases (MEK) | EXELIXIS, INC. (US) | 2011-08-16 | — | — | US | claimed |