SCHEMBL22993014

SCHEMBL22993014

CC(C)(C)c1ccc(-c2ccc3c(-c4cccc5ccccc45)c4ccccc4c(-c4ccc(C(F)(F)F)cc4)c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 1/20 0.39
KCNQ2 O43526 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
KIF11 P52732 3/20 0.37
PSD A5PKW4 1/20 0.36
CCR4 P51679 1/20 0.35
P2RY14 Q15391 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
ESR1 P03372 2/20 0.34
BACE1 P56817 1/20 0.34
NR1I2 O75469 1/20 0.34
LMNA P02545 1/20 0.34
ADRA2A P08913 1/20 0.34
CYP2D6 P10635 1/20 0.34
ACHE P22303 1/20 0.34
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993275 0.97 KCNQ3 (0.40) KCNQ3KCNQ2GPR84KIF11PSD
SCHEMBL22992995 0.92 CYP1A1 (0.40) KCNQ3KCNQ2GPR84KIF11CA12
SCHEMBL22993304 0.91 KIF11 (0.44) KCNQ3KCNQ2KIF11PSDP2RY14
SCHEMBL22993331 0.90 ENPP1 (0.43) KCNQ3KCNQ2KIF11PSDP2RY14
SCHEMBL22993372 0.90 GPR84 (0.38) KCNQ3KCNQ2GPR84PSDCCR4
SCHEMBL22993330 0.89 ENPP1 (0.42) KCNQ3KCNQ2KIF11PSDP2RY14
SCHEMBL22993329 0.89 ENPP1 (0.42) KCNQ3KCNQ2KIF11PSDP2RY14
SCHEMBL22993148 0.88 GPR84 (0.43) GPR84KIF11P2RY14TRPV1ESR1
SCHEMBL22993255 0.88 CA12 (0.41) KCNQ3KCNQ2KIF11PSDP2RY14
SCHEMBL22993083 0.88 ENPP1 (0.42) KCNQ3KCNQ2KIF11PSDP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed