Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22990322 | 1.00 | L3MBTL1 (0.40) | L3MBTL1ROCK2ROCK1ACACBACACA | |
| SCHEMBL22995195 | 0.85 | CACNA1I (0.40) | — | |
| SCHEMBL22990325 | 0.81 | EGFR (0.35) | ROCK2ROCK1 | |
| SCHEMBL22978636 | 0.77 | P2RX3 (0.37) | — | |
| SCHEMBL30525606 | 0.77 | P2RX3 (0.37) | — | |
| SCHEMBL21859435 | 0.76 | P2RX3 (0.41) | — | |
| SCHEMBL22978515 | 0.73 | P2RX3 (0.37) | — | |
| SCHEMBL4566147 | 0.72 | CACNA1I (0.60) | ACACBACACA | |
| SCHEMBL588472 | 0.71 | APLNR (0.48) | L3MBTL1ACACBACACA | |
| SCHEMBL12069877 | 0.71 | APLNR (0.48) | L3MBTL1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028806-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |