Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300517 | 0.89 | PTGS2 (0.41) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL2302364 | 0.88 | USP2 (0.36) | EIF2AK2HTR6ALOX5CA1CA2 | |
| SCHEMBL2302226 | 0.88 | CA1 (0.34) | EIF2AK2CA12CA1CA2CA9 | |
| SCHEMBL2301215 | 0.88 | CA2 (0.37) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL2237662 | 0.88 | PTGS2 (0.37) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL2305060 | 0.88 | CA1 (0.40) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL2303927 | 0.87 | EIF2AK2 (0.43) | EIF2AK2HTR6ALOX5ALOX5APFEN1 | |
| SCHEMBL2302715 | 0.87 | PTGS2 (0.45) | EIF2AK2ALOX5CA12CA1CA2 | |
| SCHEMBL2303487 | 0.87 | PTGS2 (0.45) | HTR6ALOX5PTGS2 | |
| SCHEMBL2303165 | 0.85 | CA12 (0.39) | EIF2AK2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |