Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301613 | 0.88 | TGFBR1 (0.42) | ALDH1A1LMNAHSD17B10CA1CA2 | |
| SCHEMBL2299883 | 0.88 | EIF2AK2 (0.41) | EIF2AK2CA1CA2ALOX5HTR6 | |
| SCHEMBL2302715 | 0.83 | PTGS2 (0.45) | EIF2AK2CA1CA2ALOX5 | |
| SCHEMBL2303487 | 0.83 | PTGS2 (0.45) | ALDH1A1LMNAALOX5HTR6MAPT | |
| SCHEMBL2301546 | 0.81 | ACVR1 (0.40) | CA1CA2 | |
| SCHEMBL2300248 | 0.80 | NISCH (0.37) | ALOX5MAPT | |
| SCHEMBL2301153 | 0.78 | CA1 (0.43) | CA1CA2MAPTF10 | |
| SCHEMBL2300656 | 0.78 | TGFBR1 (0.40) | ALDH1A1LMNAHSD17B10ALOX5HTR6 | |
| SCHEMBL2300517 | 0.78 | PTGS2 (0.41) | ALDH1A1CA1CA2 | |
| SCHEMBL2298553 | 0.77 | PDPK1 (0.45) | ALDH1A1KDM4ELMNAHPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |