Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303196 | 0.89 | PTGS2 (0.44) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL2301215 | 0.89 | CA2 (0.37) | PTGS2CA1CA2CA4CA12 | |
| SCHEMBL2305060 | 0.89 | CA1 (0.40) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL2237662 | 0.89 | PTGS2 (0.37) | PTGS2CA1CA2CA12CA9 | |
| SCHEMBL2302226 | 0.89 | CA1 (0.34) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL2299883 | 0.89 | EIF2AK2 (0.41) | PTGS2CA1CA2CA12CA9 | |
| SCHEMBL2307068 | 0.88 | TDO2 (0.40) | ALDH1A1POLBTDO2ALOX5APFEN1 | |
| SCHEMBL2303165 | 0.87 | CA12 (0.39) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2301153 | 0.86 | CA1 (0.43) | PTGS2CA1CA2CA4CA7 | |
| SCHEMBL2303495 | 0.85 | PTGES2 (0.37) | ALDH1A1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |