Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LCAT | P04180 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986575 | 0.78 | CRBN (0.41) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27746036 | 0.77 | KMT2A (0.36) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27860937 | 0.75 | GRM4 (0.36) | MAPTPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL23005388 | 0.72 | MALT1 (0.42) | SMN1; SMN2TRPV1 | |
| SCHEMBL9110156 | 0.71 | P2RX7 (0.43) | MAPTSMN1; SMN2ALDH1A1CNR2KDM4E | |
| SCHEMBL9105776 | 0.71 | P2RX7 (0.43) | MAPTSMN1; SMN2ALDH1A1CNR2KDM4E | |
| SCHEMBL27562880 | 0.70 | NOTUM (0.46) | MAPTALDH1A1NPC1GAA | |
| SCHEMBL27725203 | 0.70 | CNR2 (0.37) | MAPTSMN1; SMN2PANK3DPP4CNR2 | |
| SCHEMBL11111594 | 0.70 | ALOX5 (0.40) | ALDH1A1GAA | |
| SCHEMBL9107214 | 0.69 | ADRA1A (0.48) | MAPTSMN1; SMN2CNR2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003962-A1 | PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS | Gharda Chemicals Limited (IN) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021033165-A1 | PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS | GHARDA CHEMICALS LIMITED (IN) | 2021-02-25 | — | — | WO | disclosed |
| WO-2021033166-A1 | PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS | GHARDA CHEMICALS LIMITED (IN) | 2021-02-25 | — | — | WO | disclosed |