SCHEMBL23009458

SCHEMBL23009458

CCC(CC)C(=O)CC(=O)C(C)(C)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.37
CA1 P00915 4/20 0.37
USP2 O75604 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KCNJ11 Q14654 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23009415 0.89 CA1 (0.33) CA2CA1USP2TSHR
SCHEMBL23009499 0.83 CA2 (0.39) CA2CA1USP2TSHRMAPK1
SCHEMBL23009476 0.82
SCHEMBL22431436 0.81 FAAH (0.40) CA2CA1USP2TSHRKMT2A
SCHEMBL22974991 0.79
SCHEMBL409671 0.79 USP2 (0.39) CA2CA1USP2TSHRMAPK1
SCHEMBL23009674 0.78 USP2 (0.33) CA2CA1USP2TSHR
SCHEMBL23009526 0.78 LIPA (0.32) KMT2A
SCHEMBL23009390 0.78 USP2 (0.35) CA2CA1USP2TSHRKMT2A
SCHEMBL23009651 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-06 US disclosed
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-26 US disclosed
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-20220077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-10 US disclosed
US-20210101921-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 US disclosed
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
EP-3778614-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OTC, OCIAD1 CA2 4769/4885CA1 4867/4885USP2 4063/4885
US-20210101921-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CXXC4, L1CAM, CTCF CA2 1386/4885CA1 636/4885USP2 3573/4885
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, OSBP CA2 3390/4885CA1 2941/4885USP2 4437/4885
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 CA2 4159/4885CA1 4411/4885USP2 4743/4885
US-20220077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, ODC1, OTC CA2 4780/4885CA1 4873/4885USP2 4214/4885
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, TRPA1 CA2 3264/4885CA1 4681/4885USP2 4835/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP CA2 4118/4885CA1 4522/4885USP2 4825/4885
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM CA2 2676/4885CA1 1946/4885USP2 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.