SCHEMBL23009477

SCHEMBL23009477

CC(C)(C(=O)CC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.38
CES1 P23141 9/20 0.37
CES2 O00748 5/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PLOD2 O00469 3/20 0.36
PLOD3 O60568 2/20 0.35
PLOD1 Q02809 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23009526 0.92 LIPA (0.32) FAAHCES1CES2MEN1CYP1A2
SCHEMBL23176760 0.85 KMT2A (0.30) KMT2A
SCHEMBL183178 0.81 PLOD2 (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL23009420 0.80 MGAM (0.35) MEN1KMT2A
SCHEMBL23009456 0.79 FAAH (0.30) FAAH
SCHEMBL6912868 0.79 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL77034 0.79 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL23009373 0.79 PLOD2 (0.43) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8070156 0.79 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL11515923 0.79 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-06 US disclosed
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-26 US disclosed
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-20220077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-10 US disclosed
US-20210101921-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-08 US disclosed
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
EP-3778614-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212207-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OTC, OCIAD1 FAAH 2794/4885CES1 1882/4885CES2 419/4885
US-20210101921-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CXXC4, L1CAM, CTCF FAAH 4464/4885CES1 4524/4885CES2 1188/4885
US-20210095196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, OSBP FAAH 2374/4885CES1 3107/4885CES2 1326/4885
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 FAAH 2288/4885CES1 1919/4885CES2 757/4885
US-20220077409-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, ODC1, OTC FAAH 3061/4885CES1 2293/4885CES2 544/4885
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, TRPA1 FAAH 2272/4885CES1 2681/4885CES2 1312/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP FAAH 2447/4885CES1 2071/4885CES2 521/4885
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM FAAH 3300/4885CES1 3473/4885CES2 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.