Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237662 | 0.90 | PTGS2 (0.37) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL2304343 | 0.88 | CCNA2 (0.33) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL2300277 | 0.86 | CA12 (0.36) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL2302290 | 0.86 | ACVR1 (0.39) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL2299883 | 0.85 | EIF2AK2 (0.41) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL2301546 | 0.85 | ACVR1 (0.40) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL2300517 | 0.84 | PTGS2 (0.41) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL2300496 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL2300991 | 0.83 | CA1 (0.38) | ALDH1A1LMNAL3MBTL1ALOX5CA12 | |
| SCHEMBL2303165 | 0.83 | CA12 (0.39) | ALDH1A1LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |