Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023602 | 0.83 | HTR6 (0.41) | PTGS2MBNL1HTR6ADORA2AADORA1 | |
| SCHEMBL23023571 | 0.81 | ADORA2A (0.40) | PTGS2MBNL1HTR6ADORA2AADORA1 | |
| SCHEMBL29703800 | 0.80 | DHODH (0.41) | PTGS2MBNL1HTR6ADORA2AADORA1 | |
| SCHEMBL23013548 | 0.80 | DHODH (0.41) | PTGS2MBNL1HTR6ADORA2AADORA1 | |
| SCHEMBL23013511 | 0.75 | ALDH1A1 (0.44) | NPC1MAPTNPSR1ALDH1A1TP53 | |
| SCHEMBL29703797 | 0.75 | ALDH1A1 (0.44) | NPC1MAPTNPSR1ALDH1A1TP53 | |
| SCHEMBL15306534 | 0.74 | HTR6 (0.38) | PTGS2HTR6NPC1MAPTNPSR1 | |
| SCHEMBL19413049 | 0.71 | ALDH1A1 (0.41) | PTGS2HTR6ADORA2AADORA1NPC1 | |
| SCHEMBL23023590 | 0.68 | PTGS2 (0.44) | PTGS2HTR6ADORA2AADORA1ADORA2B | |
| SCHEMBL23023565 | 0.65 | PTGS2 (0.42) | PTGS2HTR6ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | PTGS2 3812/4885MBNL1 4024/4885HTR6 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.