SCHEMBL2302753

SCHEMBL2302753

COc1[c]c(OC)c(C)c(OC)c1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.38
CYP3A4 P08684 3/20 0.32
MAPT P10636 2/20 0.32
CA9 Q16790 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306800 0.80 TUBB1 (0.31) ACHE
SCHEMBL744322 0.80 ACHE (0.44) ACHECYP3A4MAPTCA9MEN1
SCHEMBL9444241 0.77 CYP3A4 (0.40) ACHECYP3A4MAPTCA9MEN1
SCHEMBL2828160 0.77 GAA (0.32) ACHECYP3A4MAPTCA9
SCHEMBL2304755 0.74 ALDH1A1 (0.36) CYP3A4PTGS2
SCHEMBL2862955 0.72 KDM4E (0.37) CYP3A4MAPTKMT2A
SCHEMBL7679493 0.71 ACHE (0.34) ACHE
SCHEMBL28136118 0.71 PDE4B (0.42) CYP3A4MAPTCA9
SCHEMBL16071623 0.70 ACHE (0.52) ACHECYP3A4MAPTCA9MEN1
SCHEMBL28412483 0.70 PKM (0.43) CYP3A4MAPTMEN1KMT2APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190912-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 日本ポリケム株式会社 2023-10-05 WO disclosed
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
WO-2023033030-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 国立大学法人 東京大学 2023-03-09 WO disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
CN-113874402-A Polar group-containing olefin copolymer 国立大学法人东京大学 2021-12-31 CN disclosed
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2016-08-18 US disclosed
EP-3050892-A1 IMINE COMPOUND AND NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2016-08-03 EP disclosed
EP-2351761-B1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX JAPAN POLYPROPYLENE CORP (JP) 2015-12-02 EP disclosed
EP-2351761-A1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX Japan Polypropylene Corporation (JP) 2011-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER ODC1, MACF1, MOGAT2 ACHE 3805/4885CYP3A4 122/4885MAPT 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.