Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502441 | 0.83 | ALDH1A1 (0.48) | NOTUMPTPN1CA12CA1CA2 | |
| SCHEMBL542210 | 0.83 | CA1 (0.57) | PTPN1HKDC1CA12CA1CA2 | |
| SCHEMBL5586280 | 0.83 | KDM4E (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2358109 | 0.82 | NOTUM (0.53) | NOTUMCCR6HKDC1CA12CA1 | |
| SCHEMBL3542900 | 0.82 | PTPN1 (0.57) | PTPN1MAPTELANEMEN1KMT2A | |
| SCHEMBL256770 | 0.81 | NOTUM (0.51) | NOTUMCCR6HKDC1CA12CA1 | |
| SCHEMBL2310555 | 0.81 | P4HB (0.52) | NOTUMCCR6HKDC1CA12CA1 | |
| SCHEMBL29715212 | 0.81 | NOTUM (0.51) | NOTUMCCR6HKDC1CA12CA1 | |
| SCHEMBL9107524 | 0.80 | KDM4E (0.49) | NOTUMCA12CA1CA2CA7 | |
| SCHEMBL6478663 | 0.80 | XDH (0.57) | PTPN1CCR6HKDC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053979-A1 | MACROCYCLIC TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053979-A1 | MACROCYCLIC TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | TLR7, TLR9, TLR1 | NOTUM 4745/4885PTPN1 522/4885CCR6 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.