Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158274 | 0.90 | MEN1 (0.36) | MEN1KMT2ATDP1SMN1; SMN2GAA | |
| SCHEMBL23028672 | 0.84 | ADRA2A (0.33) | MEN1KMT2AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028685 | 0.84 | ALOX15 (0.33) | MEN1KMT2AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL4110620 | 0.82 | GAA (0.38) | MEN1KMT2ATDP1SMN1; SMN2GAA | |
| SCHEMBL23028690 | 0.81 | ALOX15 (0.35) | MEN1KMT2AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028712 | 0.81 | ALDH1A1 (0.33) | MEN1KMT2AALOX15TDP1CYP1A2 | |
| SCHEMBL28195253 | 0.79 | NAAA (0.44) | MEN1KMT2ATDP1GAAPOLB | |
| SCHEMBL17754024 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL26033273 | 0.79 | TSHR (0.46) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL27364282 | 0.79 | GAA (0.33) | SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034548-A1 | MITOCHONDRIAL MODULATION TO IMPROVE METABOLIC SYNDROME DURING AGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |