Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028672 | 0.87 | ADRA2A (0.33) | TSHRKDM4EADRA2AADRA1AMAPT | |
| SCHEMBL17754024 | 0.86 | ALDH1A1 (0.43) | KDM4EADRA2AADRA1AMAPTBLM | |
| SCHEMBL23028712 | 0.84 | ALDH1A1 (0.33) | KDM4EADRA2AADRA1AMAPTKMT2A | |
| SCHEMBL4103385 | 0.83 | TSHR (0.50) | TSHRLMNAKDM4EMAPTKMT2A | |
| SCHEMBL17753849 | 0.79 | MTNR1A (0.34) | TSHRKMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL23028685 | 0.79 | ALOX15 (0.33) | TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23028673 | 0.79 | MEN1 (0.33) | TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4103840 | 0.79 | TSHR (0.54) | TSHRLMNAKMT2AMEN1CA12 | |
| SCHEMBL23028711 | 0.79 | ALOX15 (0.36) | TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4093088 | 0.78 | TSHR (0.52) | TSHRLMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230264-A2 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DESEASES | Alkermes Pharma Ireland Limited (IE) | 2023-08-23 | — | — | EP | disclosed |