Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
| ▸ | S100A9 | P06702 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265828 | 0.81 | XDH (0.41) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL2401423 | 0.78 | KMT2A (0.46) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL29464288 | 0.78 | KMT2A (0.46) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL21287682 | 0.77 | ALDH1A1 (0.35) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL25695712 | 0.77 | ALDH1A1 (0.54) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL30989056 | 0.77 | ALDH1A1 (0.35) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL24533739 | 0.77 | NUDT1 (0.36) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1801013 | 0.76 | LMNA (0.39) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1496403 | 0.76 | TDP1 (0.39) | CSNK1A1CLK4ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL19654457 | 0.75 | KMT2A (0.55) | CSNK1A1CLK4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032004-A9 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-03-25 | — | — | WO | disclosed |
| WO-2021032004-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-02-25 | — | — | WO | disclosed |