Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300883 | 0.80 | LOXL2 (0.47) | PRSS1F2PRSS2PRSS3 | |
| SCHEMBL3462583 | 0.78 | CA2 (0.50) | CA2CAMK2APRSS1KLK1TMPRSS2 | |
| SCHEMBL21223499 | 0.78 | CA2 (0.50) | CA2CAMK2APRSS1KLK1TMPRSS2 | |
| SCHEMBL3462585 | 0.78 | CA2 (0.50) | CA2CAMK2APRSS1KLK1TMPRSS2 | |
| SCHEMBL22647077 | 0.76 | CA2 (0.48) | CA2CAMK2APRSS1KLK1TMPRSS2 | |
| SCHEMBL21300881 | 0.76 | TPSAB1 (0.50) | CA2PRSS1ITGB3ITGA2BLMNA | |
| SCHEMBL18891357 | 0.75 | KMT2A (0.48) | GAATSHRF2L3MBTL1SMN1; SMN2 | |
| SCHEMBL22815269 | 0.73 | KDM1A (0.48) | CA2LMNAGAAHTTKDM4E | |
| SCHEMBL23032115 | 0.73 | L3MBTL1 (0.58) | CA2LMNANR1H4EPHX2L3MBTL1 | |
| SCHEMBL4022608 | 0.73 | PLA2G10 (0.61) | CA2CAMK2APRSS1KLK1TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |