Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031877 | 0.86 | PYCR1 (0.41) | NSD2MCHR1RAB9AKMT2AMEN1 | |
| SCHEMBL22044273 | 0.78 | GRIN2B (0.44) | RAB9AKMT2A | |
| SCHEMBL23031798 | 0.77 | HDAC1 (0.39) | MCHR1HDAC6HDAC1HDAC3ALDH1A1 | |
| SCHEMBL23032115 | 0.76 | L3MBTL1 (0.58) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2164868 | 0.75 | NSD2 (0.64) | NSD2MCHR1HDAC6HDAC1RAB9A | |
| SCHEMBL5643054 | 0.75 | KMT2A (0.68) | NSD2MCHR1HDAC6HDAC1RAB9A | |
| SCHEMBL23031878 | 0.75 | LMNA (0.44) | HDAC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5646698 | 0.74 | NSD2 (0.68) | NSD2MCHR1HDAC6HDAC1RAB9A | |
| SCHEMBL30131237 | 0.74 | NSD2 (0.68) | NSD2MCHR1HDAC6HDAC1RAB9A | |
| SCHEMBL5644792 | 0.74 | LIMK2 (0.70) | NSD2HDAC6HDAC1LIMK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034924-A1 | TRANS-CYCLOOCTENE LABELED ANTISENSE OLIGONUCLEOTIDES, RADIO LABELED TETRAZINE AND METHODS | BIOGEN MA INC. (US) | 2021-02-25 | — | — | WO | disclosed |