Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 5/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230334 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDGFERPGRSTAT3 | |
| SCHEMBL10177392 | 0.91 | PGR (0.41) | ALDH1A1PGRSTAT3AKR1C3LTC4S | |
| SCHEMBL231299 | 0.90 | ALDH1A1 (0.40) | ALDH1A1HPGDGFERPGRSTAT3 | |
| SCHEMBL231300 | 0.90 | ALDH1A1 (0.40) | ALDH1A1HPGDGFERPGRSTAT3 | |
| SCHEMBL231165 | 0.89 | STAT3 (0.40) | PGRSTAT3AKR1C3LTC4SUTS2R | |
| SCHEMBL231166 | 0.89 | STAT3 (0.40) | PGRSTAT3AKR1C3LTC4SUTS2R | |
| SCHEMBL233238 | 0.86 | SRD5A2 (0.51) | HPGDPGRSTAT3AKR1C3LTC4S | |
| SCHEMBL10176169 | 0.84 | PGR (0.43) | PGRSTAT3AKR1C3LTC4SUTS2R | |
| SCHEMBL2743161 | 0.81 | LMNA (0.48) | HPGDLTC4SSRD5A2LMNAL3MBTL1 | |
| SCHEMBL2743160 | 0.79 | MRGPRX4 (0.45) | PGRAKR1C3LTC4SSRD5A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341371-A | As LTC4Bis-aromatic compounds as synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-01 | — | — | CN | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | ALDH1A1 453/4885HPGD 169/4885GFER 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.