Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300517 | 0.84 | PTGS2 (0.41) | ALDH1A1POLBPTGS2ALOX5APFEN1 | |
| SCHEMBL2301170 | 0.83 | CA2 (0.40) | TSHR | |
| SCHEMBL2302226 | 0.83 | CA1 (0.34) | LMNAALDH1A1PTGS2ALOX5APFEN1 | |
| SCHEMBL2301215 | 0.83 | CA2 (0.37) | PTGS2ALOX5APFEN1 | |
| SCHEMBL2237662 | 0.83 | PTGS2 (0.37) | PTGS2 | |
| SCHEMBL2305060 | 0.83 | CA1 (0.40) | PTGS2 | |
| SCHEMBL2299883 | 0.83 | EIF2AK2 (0.41) | PTGS2ALOX5APFEN1 | |
| SCHEMBL2301951 | 0.82 | CA2 (0.41) | — | |
| SCHEMBL2300359 | 0.81 | CA2 (0.41) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2303165 | 0.81 | CA12 (0.39) | LMNAALDH1A1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |