Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301951 | 0.97 | CA2 (0.41) | CA2SMN1; SMN2PDPK1CA1CA12 | |
| SCHEMBL2300359 | 0.96 | CA2 (0.41) | CA2SMN1; SMN2PDPK1CA1CA12 | |
| SCHEMBL2299463 | 0.87 | CA12 (0.41) | CA2CA1CA12CA9GPR84 | |
| SCHEMBL2305006 | 0.84 | PDIA6 (0.40) | CA2CA1CA12CA9GPR84 | |
| SCHEMBL2237662 | 0.83 | PTGS2 (0.37) | CA2SMN1; SMN2CA1CA12CA9 | |
| SCHEMBL2304022 | 0.83 | L3MBTL1 (0.37) | TSHR | |
| SCHEMBL2303830 | 0.83 | LMNA (0.35) | CA2CA1NISCHAGTR2S1PR1 | |
| SCHEMBL2300517 | 0.82 | PTGS2 (0.41) | CA2CA1CA12CA9 | |
| SCHEMBL2303165 | 0.81 | CA12 (0.39) | CA2PDPK1CA1CA12CA9 | |
| SCHEMBL2302226 | 0.81 | CA1 (0.34) | CA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536693-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | Université Laval (CA) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100840-A1 | SUBSTITUTED 2-IMIDAZOLIDONES AND ANALOGS | UNIVERSITé LAVAL (CA) | 2011-08-25 | — | — | WO | disclosed |