Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043708 | 0.92 | KEAP1 (0.63) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL11775877 | 0.83 | ADRA2C (0.79) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL23152040 | 0.83 | ADRA2C (0.79) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL23043615 | 0.82 | ADRA2C (0.61) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL5092004 | 0.82 | KEAP1 (0.60) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL14206537 | 0.79 | CYP2D6 (0.57) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL484010 | 0.79 | KEAP1 (0.95) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL30664040 | 0.79 | KEAP1 (0.87) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL29938274 | 0.79 | KEAP1 (0.95) | KEAP1ADRA2CUSP2GAAMEN1 | |
| SCHEMBL23536222 | 0.78 | LGMN (0.58) | KEAP1ADRA2CUSP2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
| WO-2021041866-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | KEAP1 3912/4885ADRA2C 2427/4885USP2 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.