SCHEMBL23045698

SCHEMBL23045698

CC(C)c1cc(C(C)C)c(S(=O)(=O)NC(c2ccccc2)c2ccccc2)c(C(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.51
TDP1 Q9NUW8 1/20 0.49
FABP4 P15090 2/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
GAA P10253 1/20 0.46
PDE4B Q07343 1/20 0.44
PLAU P00749 6/20 0.43
PLAT P00750 3/20 0.43
F10 P00742 3/20 0.43
ACLY P53396 1/20 0.43
HDAC1 Q13547 1/20 0.42
ST14 Q9Y5Y6 2/20 0.40
HPN P05981 1/20 0.40
HGFAC Q04756 1/20 0.40
PLG P00747 3/20 0.39
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23052363 0.93 NR3C1 (0.46) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL810279 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL15841579 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL2240939 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL15364299 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL18269669 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL19400681 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL15364300 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL17617915 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5
SCHEMBL15043438 0.82 NR3C1 (0.47) NR3C1TDP1FABP4FABP3FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210834-A1 RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2023-07-06 US disclosed
WO-2021039824-A1 RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR 国立大学法人 岡山大学 2021-03-04 WO disclosed
WO-2021039824-A1 RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR 国立大学法人 岡山大学 2021-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210834-A1 RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR EMG1, TRDMT1, BCDIN3D NR3C1 4731/4885TDP1 397/4885FABP4 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.