Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.53 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27786392 | 1.00 | METAP2 (0.59) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL28013759 | 0.98 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| Hydrochloric Acid SCHEMBL3585581 | 0.98 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Aminoquinoline SCHEMBL29005897 | 0.89 | LMNA (0.56) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL11889685 | 0.83 | CCR1 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL21975961 | 0.77 | NCF1 (0.63) | HTR3ANOS2 | |
| SCHEMBL806441 | 0.77 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL2115749 | 0.77 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL7453433 | 0.76 | CCR1 (0.61) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL27782197 | 0.76 | CCR1 (0.61) | METAP2CCR1RAB9ACCR5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666770-A | Chiral tridentate anionic ligand containing oxazoline fragment and synthesis method and application thereof | 武汉理工大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118221661-A | Squaric acid amide fluorescent probe based on thiophenyl quinoline for identifying adenosine triphosphate and preparation method thereof | 常州大学 | 2024-06-21 | — | — | CN | claimed |
| CN-117447517-A | Novel tridentate pincer ligand, ruthenium complex, preparation method thereof and application thereof in alcohol dehydrogenation preparation of ester | 中国科学院宁波材料技术与工程研究所 | 2024-01-26 | — | — | CN | claimed |
| CN-117430484-A | Polyester hydrogenation degradation method | 中国科学院宁波材料技术与工程研究所 | 2024-01-23 | — | — | CN | claimed |
| CN-117362329-A | Preparation method and application of NNO tridentate coordination metal catalyst based on quinoline skeleton | 青岛科技大学 | 2024-01-09 | — | — | CN | claimed |
| CN-113462188-B | Pigment yellow 138 easy to disperse in weak solvent and preparation method thereof | 潍坊泰兴生物化工有限责任公司 | 2023-12-01 | — | — | CN | claimed |
| CN-116726997-A | Preparation method of amino acid functionalized column [5] aromatic hydrocarbon supermolecule chiral catalyst | 广西大学 | 2023-09-12 | — | — | CN | claimed |
| CN-113881242-B | Preparation method of pigment yellow PY138 product with low yield value for iron printing ink | 潍坊泰兴生物化工有限责任公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115850337-A | Tridentate pincerlike manganese complex, preparation method thereof and application thereof in alcohol dehydro-olefination reaction | 中国科学院宁波材料技术与工程研究所 | 2023-03-28 | — | — | CN | claimed |
| CN-110105337-B | Quinoline triarylamine and preparation method thereof | 湖南大学 | 2022-12-23 | — | — | CN | claimed |
| US-20060189604-A1 | Compounds | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | claimed |
| CN-1763013-A | 8-amidoquinaldine production method | GAOYOU AUX Y FACTORY (CN) | 2006-04-26 | — | — | CN | claimed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | claimed |
| US-20050234108-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-20 | — | — | US | claimed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | claimed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | claimed |
| US-6121452-A | REACTING A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND WITH AN AROMATIC DICARBOXYLIC ACID OR AN ANHYDRIDE THEREOF IN AN ORGANIC SOLVENT IN THE PRESENCE OF AN UNSUBSTITUTED PHENOL OR NAPHTHOL OR MIXTURE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | claimed |
| US-5342950-A | Reacting a methyl-substituted heterocyclic compound with an anhydride of an aromatic dicarboxylic acid in an alkyl benzoate solvent | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | claimed |
| EP-0463477-B1 | Method of preparation of quinophthalones | BASF AG (DE) | 1994-03-16 | — | — | EP | claimed |
| US-5106980-A | PREPARATION OF QUINOPHTHALONES | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234108-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions | DPP8, DPP4, DPP7 | METAP2 30/4885CCR1 911/4885RAB9A 2916/4885 |
| US-20060189604-A1 | Compounds | ELANE, PIGS, SDHA | METAP2 3046/4885CCR1 73/4885RAB9A 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.