Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777733 | 0.83 | NOS3 (0.35) | NOS3NOS2NOS1HRH4 | |
| SCHEMBL29491137 | 0.83 | NOS3 (0.35) | NOS3NOS2NOS1HRH4 | |
| SCHEMBL18978721 | 0.81 | USP2 (0.37) | TSHRUSP2ALDH1A1GAAPKM | |
| SCHEMBL18978703 | 0.81 | USP2 (0.37) | TSHRUSP2ALDH1A1GAAPKM | |
| SCHEMBL20621321 | 0.80 | NOS2 (0.48) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL25887311 | 0.76 | HTR2A (0.36) | NOS3NOS2NOS1 | |
| SCHEMBL20621434 | 0.76 | L3MBTL1 (0.38) | ALDH1A1GAANOS3NOS2NOS1 | |
| SCHEMBL24574394 | 0.76 | USP2 (0.30) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL21883684 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GAAHPGDHSD17B10HRH4 | |
| SCHEMBL19780267 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GAAHPGDHSD17B10HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10937976-B2 | Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues | PDCD1, PDCD11, TYMP | TSHR 1135/4885USP2 4580/4885ALDH1A1 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.