Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666838 | 0.89 | CSNK2A2 (0.32) | CSNK2A2CSNK2A1RIPK1POLRMTFBP1 | |
| SCHEMBL18666928 | 0.83 | POLRMT (0.34) | CSNK2A2CSNK2A1RIPK1POLRMTFBP1 | |
| SCHEMBL20762571 | 0.83 | POLRMT (0.34) | CSNK2A2CSNK2A1RIPK1POLRMTFBP1 | |
| SCHEMBL21284180 | 0.83 | CYP3A4 (0.35) | RIPK1 | |
| SCHEMBL24789459 | 0.82 | RIPK1 (0.33) | RIPK1POLRMT | |
| SCHEMBL22393573 | 0.82 | TMPRSS2 (0.32) | RIPK1 | |
| SCHEMBL10154198 | 0.82 | TMPRSS2 (0.36) | CSNK2A2CSNK2A1RIPK1POLRMTFBP1 | |
| SCHEMBL22096277 | 0.81 | AXL (0.30) | — | |
| SCHEMBL10154374 | 0.80 | TMPRSS2 (0.33) | CSNK2A2CSNK2A1RIPK1POLRMT | |
| SCHEMBL14845681 | 0.79 | TMPRSS2 (0.34) | CSNK2A2CSNK2A1RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |