Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15186243 | 0.77 | L3MBTL1 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL15933317 | 0.77 | HSD17B1 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL15030378 | 0.76 | TDP1 (0.41) | — | |
| SCHEMBL18402879 | 0.74 | RAPGEF4 (0.36) | — | |
| SCHEMBL17787348 | 0.73 | DAO (0.38) | — | |
| SCHEMBL11947811 | 0.72 | PRKCI (0.30) | — | |
| SCHEMBL15658672 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL16492215 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL11684162 | 0.71 | TP53 (0.48) | — | |
| SCHEMBL38658544 | 0.69 | RXRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786156-A1 | 10H-PHENOTHIAZINE FERROPTOSIS INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Chengdu Henghao Investment Co. Limited (CN) | 2021-03-03 | — | — | EP | disclosed |