Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603811 | 0.80 | DAO (0.51) | DAORXRARXRBRXRGPTGDR2 | |
| SCHEMBL15933317 | 0.80 | HSD17B1 (0.35) | — | |
| SCHEMBL15186243 | 0.80 | L3MBTL1 (0.33) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL18402879 | 0.77 | RAPGEF4 (0.36) | MAPTPOLBMEN1HSP90AA1KMT2A | |
| SCHEMBL3134248 | 0.76 | ALDH1A1 (0.43) | KIF11 | |
| SCHEMBL12603784 | 0.76 | RXRA (0.55) | DAORXRARXRBRXRGMAPT | |
| SCHEMBL14752089 | 0.75 | PPARD (0.43) | DAOMAPTMEN1KMT2APPARG | |
| SCHEMBL26437524 | 0.75 | ALDH1A1 (0.42) | BCHEACHEKIF11 | |
| SCHEMBL23048288 | 0.73 | NOS3 (0.33) | — | |
| SCHEMBL13248336 | 0.72 | SLC6A4 (0.42) | DAORXRARXRBRXRGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353133-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-31 | — | — | US | disclosed |