Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051110 | 0.83 | HTT (0.47) | ATML3MBTL1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23051111 | 0.83 | HDAC3 (0.60) | L3MBTL1ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL21249722 | 0.82 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL23051157 | 0.82 | HTT (0.46) | ATML3MBTL1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL23051139 | 0.82 | MEN1 (0.43) | ATML3MBTL1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14723177 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1LMNAPAX8MEN1 | |
| SCHEMBL3083874 | 0.80 | ALDH1A1 (0.52) | L3MBTL1MTNR1AMTNR1BALDH1A1RAB9A | |
| SCHEMBL23051105 | 0.79 | CACNA1G (0.41) | L3MBTL1MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL24497081 | 0.78 | POLB (0.41) | MTNR1AMTNR1BALDH1A1RAB9ANPC1 | |
| SCHEMBL24497225 | 0.78 | KDM4E (0.44) | MTNR1AMTNR1BALDH1A1LMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041583-A1 | COMPOUNDS TO IDENTIFY BETA-LACTAMASES, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |